Scalp Electroacupuncture Promotes Angiogenesis after Stroke in Rats by Activation of Wnt/β-Catenin Signal Pathway

Figure 2

Effect of scalp electroacupuncture on brain tissues after cerebral ischemia-reperfusion injury with DKK1. (a) Cerebral tissues from each group were sectioned into 2-mm slices and then processed for triphenyl tetrazolium chloride (TTC) staining. Normal areas of the brain were stained deep red, and the infarct areas remained unstained. (b) The volume of cerebral infarction was shown. ^★ vs. the model group; ^▲ vs. the DKK1 group. (c) The representative results of western blots together with quantitative analyses in the expression level of Wnt3a, β-catenin, VEGF, and Ang2 in the sham, model, DKK1, AC, and AC + DKK1 groups on day 7 postinjury. ^★★ vs. the model group; vs. the AC + DKK1 group; ^▲▲ vs. the DKK1 group. (d) mRNA expression levels of Wnt3a and β-catenin in the sham, model, DKK1, AC, and AC + DKK1 groups on day 7 postinjury. ^★★★, ^★★, and ^★ vs. the model group. (e) mRNA expression levels of VEGF and Ang2 in the sham, model, DKK1, AC, and AC + DKK1 groups on day 7 postinjury. vs. the sham group; ^★, ^★★, and ^★★★ vs. the model group; vs. the AC + DKK1 group; ^▲▲ vs. the DKK1 group.

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