Lignans from Mosla scabra Ameliorated Influenza A Virus-Induced Pneumonia via Inhibiting Macrophage Activation

Figure 1

MSTL ameliorated IAV-induced lung inflammation in mice. (a) The histopathological results of lung tissues observed by the optical microscope (scale bar, 100 μm). (b) The histopathological characteristics scored by using the following grading scale, in which the bigger the score was, the more severity of lung inflammatory response was. (c) The viral loads of the lung tissues detected by qRT-PCR. The average viral loads decreased with increase of Ct values. ND, not detected. (d) The serum levels of TNF-α and IL-1β detected by ELISA. All data are shown as mean ± SEM (n = 8). Different letters meant significant differences () by Tukey’s test.

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