Lignans from Mosla scabra Ameliorated Influenza A Virus-Induced Pneumonia via Inhibiting Macrophage Activation

Figure 3

Inhibition of MSTL on IAV-induced pyroptosis and proinflammatory cytokine release of RAW 264.7 cells. (a) Cytotoxicities of MSTL on the proliferation of RAW 264.7 cells. (b) Inhibition of MSTL on IAV-induced pyroptosis of RAW 264.7 cells. (c) Inhibition of MSTL on the release of MCP-1, TNF-α, IL-1β, PGE₂, PLA₂, and LTB₄ in IAV-infected RAW 264.7 cells. Ribavirin, 10 μg/ml. All data are shown as mean ± SEM (n = 5). Different letters meant significant differences () by Tukey’s test.

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