Molecular Analysis of Xmn1-Polymorphic Site ´5 to Gγ of the β-Globin Gene Cluster in a Saudi Population of Jazan Region in Correlation with Hb F Expression
Table 1
Complete haemogram indices in sickle patients against the control group.
Blood parameters
Control
Hb AS
Hb SS
RBC x 109/L (±SD)
4.6 × 106 (0.5)
3.8 × 106 (0.4)
3.2 × 106 (±0.4) (a)
Hb g/dl (±SD)
15.8 (2.2) (a)
12.6 (1.1) (a)
8.1 (1.2) (a)
MCH/pg (±SD)
26.2 (1.1) (a)
26.7 (1.5) (c)
25.6 (2.1) (c)
MCHC g/dl (±SD)
37.1 (1.1) (a)
36.2 (1.6) (c)
35.6 (1.8) (c)
PCV % (±SD)
46.6 (4.2) (a)
37.0 (5.6) (a)
26.7 (4.2) (a)
MCV fl (±SD)
83.3 (5.3)
72.6 (6.5) (a)
78.2 (7.9) (a)
RDW fl (±SD)
42.1 (2.6)
43.7 (3.5)
83.8 (4.3) (a)
WBC x 109/L (±SD)
5.6 (1.7)
6.9 (1.3)
12.7 (3.2) (a)
Neut% (±SD)
47 (11)
51 (15)
62 (11) (a)
Lymph% (±SD)
33 (9)
34 (7)
28 (9)
Mono% (±SD)
8 (3.7)
8.2 (2.4)
8.9 (2.3)
Eosino% (±SD)
3.4 (1.9)
3.2 (2.1)
2.7 (2.8)
Baso% (±SD)
0.9 (1.2)
0.9 (0.7)
0.8 (0.5)
PLt x 109/L (±SD)
245 (95)
289 (114) (a)
398 (125) (a)
Key: significance determined by comparison of each group with control indices. (a) = ; Statistical significance is shown in parenthesis.
