Comparison between the Efficacy of Nigella sativa-Honey and Clotrimazole on Vulvovaginal Candidiasis: A Randomized Clinical Trial

Table 1

The comparison of mean, standard deviation, and p value for study variables in two groups (N. sativa–honey and clotrimazole).

Variables	Clotrimazole (n = 39)	N. sativa-honey (n = 40)
Age (years); mean (SD)	33.10 (7.24)	32.65 (7.21)	0.782^†
BMI; mean (SD)	26.34 (4.02)	26.66 (4.69)	0.750^†
Education; n (%)			0.566^&
High school	16 (41.0)	12 (30.0)
Diploma	13 (33.3)	17 (42.5)
Academic	10 (25.6)	11 (27.5)
Job; n (%)			0.481^&
Housewife	36 (92.3)	34 (85.0)
Employee	3 (7.7)	6 (15.0)
Husband education; n (%)			0.692^&
High school	18 (46.1)	14 (35.0)
Diploma	17 (43.6)	21 (52.5)
Academic	4 (10.3)	5 (12.5)
Economic status; n (%)			0.234^&
Weak	11 (28.2)	6 (15.0)
Moderate	26 (66.7)	29 (72.5)
Good	2 (5.1)	5 (12.5)
Menstrual cycle status; n (%)			0.808^††
Normally	27 (69.2)	29 (72.5)
Irregular	12 (30.8)	11 (27.5)
Contraceptive method; n (%)			0.964^&
OCP	4 (10.3)	4 (10.0)
IUD	4 (10.3)	2 (5.0)
Withdrawal	17 (43.6)	19 (47.5)
Condom	5 (12.8)	6 (15.0)
TL or vasectomy	3 (7.7)	4 (10.0)
Nothing	6 (15.4)	5 (12.5)
Anemia; n (%)			0.086^††
No	35 (89.7)	28 (70.0)
Yes	4 (10.3)	12 (30.0)
Underwear material; n (%)			0.138^&
Linen	34 (87.2)	29 (72.5)
Plastic	0 (0.0)	3 (7.5)
Both	5 (12.8)	8 (20.0)
Use the pool; n (%)			0.316^††
No	28 (71.8)	27 (67.5)
Yes	11 (28.2)	13 (32.5)
The number of times of intimacy with spouse per week; n (%)			0.185^&
0	3 (7.7)	5 (12.5)
1	12 (30.8)	8 (20)
2	13 (33.3)	11 (27.5)
3	7 (17.9)	4 (10.0)
≥4	4 (10.3)	12 (30.0)
Days of vaginal culture; n (%)			0.327^&
6th	14 (35.9)	13 (32.5)
7th	22 (56.4)	19 (47.5)
8th	2 (5.1)	2 (5.0)
9th	0 (0.0)	1 (2.5)
10th	1 (2.6)	5 (12.5)

Significance level: P < 0.05; ^†Independent sample t-test;^††Pearson’s chi-square test; ^&Fisher exact test; SD: Standard deviatio; BMI: body mass index.