Comparison between the Efficacy of Nigella sativa-Honey and Clotrimazole on Vulvovaginal Candidiasis: A Randomized Clinical Trial

Table 2

The comparison of the effects of N. sativa–honey and clotrimazol on VVC.

Variables	Clotrimazole (n = 39)		N. sativa- honey (n = 40)			Odds ratio (95% CI)
	No or negative	Yes or positive	No or negative	Yes or positive
Abnormal discharge; n (%)					0.025^††	5.7 (1.14, 28.38)
Before	0 (0.0)	39 (100)	0 (0.0)	40 (100)
After	30 (76.9)	9 (23.1)	38 (95.0)	2 (5.0)
Redness; n (%)					0.201^&	4.45 (0.475, 41.797)
Before	0 (0.0)	39 (100)	0 (0.0)	40 (100)
After	35 (89.7)	4 (10.3)	39 (97.5)	1 (2.5)
Itching; n (%)					0.013^††	3.942 (1.342, 11.575)
Before	0 (0.0)	39 (100)	0 (0.0)	40 (100)
After	23 (59.0)	16 (41.0)	34 (85.0)	6 (15.0)
Vaginal culture for candidiasis; n (%)					0.622^††	0.716 (0.27, 1.902)
Before	0 (0.0)	39 (100)	0 (0.0)	40 (100)
After	29 (74.4)	10 (25.6)	27 (67.5)	13 (32.5)

Significance level: P < 0.05; ^&Fisher Exact Test; ^††Pearson’s chi-square test; CI = confidence interval.