Network Pharmacology-Based Strategy to Investigate the Mechanisms of Cibotium barometz in Treating Osteoarthritis

Table 1

Prime sequences for quantitative real-time PCR and siRNA.

Gene name	Sequence (5′-to-3′)
Human MMP-1 Sense	CTGTTTTCTGGCCACAACTG
Human MMP-1 Antisense	GGAAGCCAAAGGAGCTGTAG
Human MMP-3 Sense	TTGGCCATCTCTTCCTTCAG
Human MMP-3 Antisense	GAAACCTAGGGTGTGGATGC
Human MMP-13 Sense	GTGCCCTTCTTCACACAGAC
Human MMP-13 Antisense	AGAGCAGACTTTGAGTCATTGC
Human NFκB p65 Sense	AGGAGCACAGATACCACCAAGACC
Human NFκB p65 Antisense	AAGCAGAGCCGCACAGCATTC
Human GAPDH Sense	GCACCGTCAAGGCTGAGAAC
Human GAPDH Antisense	TGGTGAAGACGCCAGTGGA
Rat MMP-1 Sense	GCTTAGCCTTCCTTTGCTGTTGC
Rat MMP-1 Antisense	GACGTCTTCACCCAAGTTGTAGTAG
Rat MMP-3 Sense	CGGTGGCTTCAGTACCTTTC
Rat MMP-3 Antisense	ACCTCCTCCCAGACCTTCA
Rat MMP-13 Sense	TGCATACGAGCATCCATCCC
Rat MMP-13 Antisense	CTCAAAGTGAACCGCAGCAC
Rat β-actin Sense	CACCCGCGAGTACAACCTTC
Rat β-actin Antisense	CCCATACCCACCATCACACC
NFκB p65 siRNA Sense	GGCGAGAGGAGCACAGAUATT
NFκB p65 siRNA Antisense	UAUCUGUGCUCCUCUCGCCTT
Negative control siRNA Sense	UUCUCCGAACGUGUCACGUTT
Negative control siRNA Antisense	ACGUGACACGUUCGGAGAATT

MMP, matrix metalloproteinase.