Jieduan–Niwan Formula Ameliorates Oxidative Stress and Apoptosis in Acute-on-Chronic Liver Failure by Suppressing HMGB1/TLR-4/NF-<i>κ</i>B Signaling Pathway: A Study In Vivo and In Vitro

<div>The mechanisms of JDNW inhibit HMGB1 overexpression and translocation, thus the oxidative stress and apoptosis are mediated by the HMGB1/TLR-4/NF-<i>κ</i>B pathway in ACLF.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 10

Figure 10: Jieduan–Niwan Formula Ameliorates Oxidative Stress and Apoptosis in Acute-on-Chronic Liver Failure by Suppressing HMGB1/TLR-4/NF-<i>κ</i>B Signaling Pathway: A Study In Vivo and In Vitro 

Figure 10 | Jieduan–Niwan Formula Ameliorates Oxidative Stress and Apoptosis in Acute-on-Chronic Liver Failure by Suppressing HMGB1/TLR-4/NF-κB Signaling Pathway: A Study In Vivo and In Vitro 