Jieduan–Niwan Formula Ameliorates Oxidative Stress and Apoptosis in Acute-on-Chronic Liver Failure by Suppressing HMGB1/TLR-4/NF-<i>κ</i>B Signaling Pathway: A Study In Vivo and In Vitro

<div>Effects of JDNW intervention on liver histopathology in ACLF rats at different time points. (a, b) Hematoxylin and eosin (H&amp;E) staining to evaluate the pathological changes in rat’s liver. Magnification 200x, 800x; scale bar: 200 <i>μ</i>m, 50 <i>μ</i>m. Infiltration of inflammatory cells (Black arrows), necrotic hepatocytes (Yellow arrows). (c) Evaluation of histopathological status (Knodell score). 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Evidence-Based Complementary and Alternative Medicine

fig2

Figure 2

Figure 2: Jieduan–Niwan Formula Ameliorates Oxidative Stress and Apoptosis in Acute-on-Chronic Liver Failure by Suppressing HMGB1/TLR-4/NF-<i>κ</i>B Signaling Pathway: A Study In Vivo and In Vitro 

Figure 2 | Jieduan–Niwan Formula Ameliorates Oxidative Stress and Apoptosis in Acute-on-Chronic Liver Failure by Suppressing HMGB1/TLR-4/NF-κB Signaling Pathway: A Study In Vivo and In Vitro 