Jieduan–Niwan Formula Ameliorates Oxidative Stress and Apoptosis in Acute-on-Chronic Liver Failure by Suppressing HMGB1/TLR-4/NF-<i>κ</i>B Signaling Pathway: A Study In Vivo and In Vitro

<div>Effects of JDNW on the expression of Bax, Bcl-2, and Caspase-3 in vitro and in vivo. (a–d) Effects of JDNW treatment at different time points on mitochondrial apoptosis-related proteins in liver tissues of ACLF rats. (e–h). Effects of JDNW serum on mitochondrial apoptosis-related proteins of L02 cells. The data on quantified protein expressions were normalized by related <i>β</i>-actin. 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Evidence-Based Complementary and Alternative Medicine

fig6

Figure 6

Figure 6: Jieduan–Niwan Formula Ameliorates Oxidative Stress and Apoptosis in Acute-on-Chronic Liver Failure by Suppressing HMGB1/TLR-4/NF-<i>κ</i>B Signaling Pathway: A Study In Vivo and In Vitro 

Figure 6 | Jieduan–Niwan Formula Ameliorates Oxidative Stress and Apoptosis in Acute-on-Chronic Liver Failure by Suppressing HMGB1/TLR-4/NF-κB Signaling Pathway: A Study In Vivo and In Vitro 