Jieduan–Niwan Formula Ameliorates Oxidative Stress and Apoptosis in Acute-on-Chronic Liver Failure by Suppressing HMGB1/TLR-4/NF-<i>κ</i>B Signaling Pathway: A Study In Vivo and In Vitro

<div>Effects of JDNW on the expression and translocation of HMGB1 in ACLF rats. (a) Immunofluorescence staining of HMGB1 at different time points. Scale bar: 100 <i>μ</i>m; HMGB1 in the cytoplasm (red arrows). (b) Western blot detection of HMGB1. (c) Ratio of HMGB1 in the cytoplasm and (d) total HMGB1 by western blot assay. (e) HMGB1 mRNA expression was detected by qRT-PCR. 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Evidence-Based Complementary and Alternative Medicine

fig7

Figure 7

Figure 7: Jieduan–Niwan Formula Ameliorates Oxidative Stress and Apoptosis in Acute-on-Chronic Liver Failure by Suppressing HMGB1/TLR-4/NF-<i>κ</i>B Signaling Pathway: A Study In Vivo and In Vitro 

Figure 7 | Jieduan–Niwan Formula Ameliorates Oxidative Stress and Apoptosis in Acute-on-Chronic Liver Failure by Suppressing HMGB1/TLR-4/NF-κB Signaling Pathway: A Study In Vivo and In Vitro 