Jieduan–Niwan Formula Ameliorates Oxidative Stress and Apoptosis in Acute-on-Chronic Liver Failure by Suppressing HMGB1/TLR-4/NF-κB Signaling Pathway: A Study In Vivo and In Vitro

Figure 9

Effect of JDNW on HMGB1/TLR-4/NF-κB pathway in ACLF rats. The protein expression levels in liver tissues of TLR-4, NF-κB P65, iNOS, and COX-2 were evaluated by western blotting. (a) Representative immunoblots. (b–e) The relative protein expression results of TLR-4, NF-κB P65, iNOS, and COX-2. Each bar represents the mean ± SD of n = 3 (, , “ns” ).

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