Ethyl Acetate Fraction of Hedyotis diffusa Willd Induces Apoptosis via JNK/Nur77 Pathway in Hepatocellular Carcinoma Cells

Figure 3

EHDW inhibited the tumorigenicity of Hep3B cells in zebrafish. Larvae were microinjected with 200 cells, and then treated with EHDW at 10, 20, and 30 μg/mL or sorafenib (0.25 μM). After 72 h, zebrafish were dehydrated and embedded in paraffin for HE staining. Bar: 50 μm. Red circles indicated tumor cells.