Effect of Integrative Chinese and Western Medicine Therapy on Long-Term Clinical Outcomes in Patients with Heart Failure: A Real-World Study Including 394 Patients
Table 1
Basic information of patients with heart failure in two groups.
Integrative therapy N = 181
Conventional therapy N = 213
Age (years)
63.98 ± 10.44
60.85 ± 11.25
0.005
Gender (male), cases (%)
107 (59.1)
141 (66.2)
0.174
Weight (kg)
71.55 ± 14.62
71.62 ± 14.59
0.964
BMI (kg·m−2)
25.48 ± 4.35
25.17 ± 3.94
0.500
Medication use (cases (%))
Diuretics
150 (82.9)
172 (80.8)
0.587
ACEI/ARB
117 (64.6)
154 (72.3)
0.099
β-Blockers
143 (79.0)
181 (85.0)
0.107
MRA
129 (71.3)
135 (63.4)
0.129
Comorbidities (cases (%))
Hypertension
122 (67.4)
139 (65.3)
0.747
Coronary artery disease
98 (54.1)
134 (62.9)
0.079
Arrhythmia
60 (33.1)
80 (37.6)
0.397
Heart valve disease
19 (10.5)
25 (11.7)
0.697
Diabetes mellitus
106 (58.6)
108 (50.7)
0.154
Renal insufficiency
76 (42.0)
45 (21.1)
<0.001
Smoking history (cases (%))
63 (34.8)
88 (41.3)
0.118
Hb (g·L−1)
127.48 ± 23.89
129.91 ± 25.19
0.330
Cr (μmol·L−1)
92.30 (72.50, 130.30)
83.90 (69.30, 107.43)
0.040
TG (mmol·L−1)
1.67 ± 0.78
1.63 ± 1.04
0.681
LDL-C (mmol·L−1)
2.41 ± 0.80
2.42 ± 0.91
0.896
Hs-CRP (mg·L−1)
6.71 (2.13, 14.54)
3.00 (1.20, 11.61)
0.007
NT-proBNP (pg·mL−1)
2455.00 (625.00, 7400.50)
1520.00 (452.00, 3594.00)
0.019
Hcy (μmol·L−1)
17.98 ± 8.50
17.64 ± 13.26
0.823
K+ (mmol·L−1)
4.06 ± 0.51
4.04 ± 0.48
0.681
Na+ (mmol·L−1)
139.69 ± 3.24
139.26 ± 3.12
0.203
Cl− (mmol·L−1)
103.14 ± 8.07
103.67 ± 4.21
0.413
Mg2+ (mmol·L−1)
0.88 ± 0.11
0.89 ± 0.10
0.362
Echocardiography index
LVEF (%)
47.45 ± 15.03
49.36 ± 14.09
0.215
LVMI (g·m−2)
122.20 ± 42.73
116.93 ± 35.26
0.239
In-hospital cardiac function class (cases (%))
0.004
I
0 (0)
0 (0)
II
19 (10.5)
27 (12.7)
III
73 (40.3)
116 (54.5)
IV
89 (49.2)
70 (32.8)
Hospital days (days)
9.76 ± 4.10
8.43 ± 4.77
0.003
analysis of indicators between patients in the integrative therapy group and conventional therapy group.