Research Article

Effect of Integrative Chinese and Western Medicine Therapy on Long-Term Clinical Outcomes in Patients with Heart Failure: A Real-World Study Including 394 Patients

Table 1

Basic information of patients with heart failure in two groups.

Integrative therapy N = 181Conventional therapy N = 213

Age (years)63.98 ± 10.4460.85 ± 11.250.005
Gender (male), cases (%)107 (59.1)141 (66.2)0.174
Weight (kg)71.55 ± 14.6271.62 ± 14.590.964
BMI (kg·m−2)25.48 ± 4.3525.17 ± 3.940.500

Medication use (cases (%))
 Diuretics150 (82.9)172 (80.8)0.587
 ACEI/ARB117 (64.6)154 (72.3)0.099
β-Blockers143 (79.0)181 (85.0)0.107
 MRA129 (71.3)135 (63.4)0.129

Comorbidities (cases (%))
 Hypertension122 (67.4)139 (65.3)0.747
 Coronary artery disease98 (54.1)134 (62.9)0.079
 Arrhythmia60 (33.1)80 (37.6)0.397
 Heart valve disease19 (10.5)25 (11.7)0.697
 Diabetes mellitus106 (58.6)108 (50.7)0.154
 Renal insufficiency76 (42.0)45 (21.1)<0.001

Smoking history (cases (%))63 (34.8)88 (41.3)0.118
Hb (g·L−1)127.48 ± 23.89129.91 ± 25.190.330
Cr (μmol·L−1)92.30 (72.50, 130.30)83.90 (69.30, 107.43)0.040
TG (mmol·L−1)1.67 ± 0.781.63 ± 1.040.681
LDL-C (mmol·L−1)2.41 ± 0.802.42 ± 0.910.896
Hs-CRP (mg·L−1)6.71 (2.13, 14.54)3.00 (1.20, 11.61)0.007
NT-proBNP (pg·mL−1)2455.00 (625.00, 7400.50)1520.00 (452.00, 3594.00)0.019
Hcy (μmol·L−1)17.98 ± 8.5017.64 ± 13.260.823
K+ (mmol·L−1)4.06 ± 0.514.04 ± 0.480.681
Na+ (mmol·L−1)139.69 ± 3.24139.26 ± 3.120.203
Cl (mmol·L−1)103.14 ± 8.07103.67 ± 4.210.413
Mg2+ (mmol·L−1)0.88 ± 0.110.89 ± 0.100.362

Echocardiography index
 LVEF (%)47.45 ± 15.0349.36 ± 14.090.215
 LVMI (g·m−2)122.20 ± 42.73116.93 ± 35.260.239

In-hospital cardiac function class (cases (%))0.004
 I0 (0)0 (0)
 II19 (10.5)27 (12.7)
 III73 (40.3)116 (54.5)
 IV89 (49.2)70 (32.8)
Hospital days (days)9.76 ± 4.108.43 ± 4.770.003

analysis of indicators between patients in the integrative therapy group and conventional therapy group.