Effectiveness of Tai Chi on Blood Pressure, Stress, Fatigue, and Sleep Quality among Chinese Women with Episodic Migraine: A Randomised Controlled Trial

Table 3

Between-group differences in blood pressure, stress, fatigue, and sleep quality at 12 weeks and 24 weeks.

Outcome^a	Between-group differences at 12 weeks		Between-group differences at 24 weeks
	Intervention vs. control	P^b	Intervention vs. control	P^b	P^c
Systolic blood pressure (mmHg)
ITT	−3.2 (−7.8 to 1.4)	0.828	−6.9 (−11.6 to −2.1)	0.020	0.020
Per-protocol	−4.0 (−9.1 to 1.1)	0.398	−7.9 (−13.6 to −2.1)	0.079	0.216
Diastolic blood pressure (mmHg)
ITT	−0.4 (−4.2 to 3.3)	0.706	−1.2 (−4.7 to 2.4)	0.296	0.524
Per-protocol	−1.5 (−5.2 to 2.1)	0.309	−2.3 (−6.5 to 1.9)	0.258	0.387
Stress
ITT	−2.4 (−4.8 to −0.0)	0.085	−1.7 (−4.7 to 1.2)	0.223	0.222
Per-protocol^d	−2.0 (−4.4 to 0.4)	0.068	−0.8 (−4.1 to 2.4)	0.411	0.214
Fatigue
ITT	−0.0 (−0.9 to 0.9)	0.989	−0.5 (−1.5 to 0.5)	0.560	0.795
Per-protocol	0.0 (−1.0 to 1.1)	0.867	−1.1 (−1.2 to 1.0)	0.301	0.583
Sleep quality
ITT	−1.3 (−2.7 to 0.1)	0.097	−1.3 (−2.8 to 0.2)	0.220	0.255
Per-protocol	−1.7 (−3.2 to −1.2)	0.298	−1.1 (−2.7 to 0.4)	0.133	0.200

^aValues are presented as mean (95% CI) for mean change between groups. ^bP values were calculated for the time × group interaction effects from baseline to 12 weeks or from the baseline to 24 weeks between groups by repeated ANCOVA; variables with significant differences between groups at the baseline were adjusted as covariates. ^cP values were calculated for the time × group interaction effects across the baseline, 12 weeks, and 24 weeks between groups by repeated ANCOVA; variables with significant differences between groups at the baseline were adjusted as covariates.