Review Article

[Retracted] Systematic Evaluation of Randomized Clinical Trials of Huangqin Tang in Combination with Mesalazine for Ulcerative Colitis

Table 1

Characteristics of the included literature.

Author, yearSample sizeDiagnostic criteriaMale%Age (years)Course of the diseaseTreatment interventionControl interventionPeriod of treatment (months)Outcome indicator
Experimental groupControl groupExperimental groupControl group

Hu et al., [14]116Clinical symptoms, colonoscopy, pathology51.7%42.37 ± 2.8742.61 ± 2.828.71 ± 2.428.94 ± 2.4HQT1+mesalazineaMesalazinea2Cure rate, total effective rate, clinical symptom score
Ding et al., [15]126Clinical symptoms, colonoscopy, pathology53.2%43.5 ± 9.642.4 ± 8.79.5 ± 3.29.2 ± 3.5HQT2+mesalazineaMesalazinea2Cure rate, total effective rate, TCM syndrome score, IL-6/10/TNF-α IgG/IgM/IgA
Yan [16]82Clinical symptoms, imaging54.9%36.68 ± 6.5236.74 ± 6.586.52 ± 3.236.47 ± 3.18HQT1+mesalazineaMesalazinea2Cure rate, total effective rate
Wang and Wang [17]78Clinical symptoms, colonoscopy57.7%35.36 ± 4.3235.18 ± 4.293.91 ± 0.453.86 ± 0.41HQT1+mesalazineMesalazine3Cure rate, total effective rate, adverse reactions
Lu [18]95Clinical symptoms, colonoscopy, pathology51.6%36.57 ± 6.5935.97 ± 6.29NANAHQT1+mesalazinebMesalazineb2IL-10/TNF-α,IgG/IgM/IgA
Yang [19]68Clinical symptoms, colonoscopy, pathology, imaging48.542.6 ± 12.741.5 ± 12.5NANAHQT2+mesalazinebMesalazineb2Cure rate, total effective rate, IL-6/10/TNF-α

“1” represents decoction of HQT, “2” represents granule of HQT; “a” represents mesalazine granules or sustained-release granules, and “b” represents mesalazine enteric-coated tablets.