[Retracted] Systematic Evaluation of Randomized Clinical Trials of Huangqin Tang in Combination with Mesalazine for Ulcerative Colitis

Table 2

GRADE summary of HQT in the UC randomized controlled trial.

			Evaluation of evidence quality
Outcome	Number of studies	Study design	Risk of bias	Inconsistency	Indirectness	Imprecision	Quality (evidence)	Importance of outcome
Cure rate	5	RCT	Serious^a	Serious^b	Not serious	Not serious	Low	Critical
Total effective rate	5	RCT	Serious^a	Not serious	Not serious	Not serious	Low	Critical
Diarrhea	2	RCT	Serious^c	Serious^d	Not serious	Not serious^gh	Low	Important
Abdominal pain	2	RCT	Serious^b	Serious^d	Not serious	Not serious^gh	Low	Important
Hematochezia	2	RCT	Serious^b	Serious^d	Not serious	Serious^gh	Low	Important
Tenesmus	2	RCT	Serious^b	Serious^d	Not serious	Serious^gh	Low	Important
TNF-α	3	RCT	Serious^e	Serious^f	Not serious	Not serious	Low	Important
IL-10	3	RCT	Serious^e	Not serious	Not serious	Not serious	Low	Important
IL-6	2	RCT	Serious^c	Not serious	Not serious	Serious^gh	Low	Important
IgM	2	RCT	Serious^c	Not serious	Not serious	Serious^gh	Low	Not important
IgG	2	RCT	Serious^c	Not serious	Not serious	Serious^gh	Low	Not important
IgA	2	RCT	Serious^c	Not serious	Not serious	Serious^gh	Low	Not important
Safety	3	RCT	Serious^e	Not serious	Not serious	Not serious	Low	Important

^aThree studies used the random number table method; it was unclear whether the blind method was used, and random conceals were not reported. ^bOne study used a significant effect description in which the requirements for clinical symptoms and colonoscopy observation met the cure criteria. ^cOne study used the random number table method; it was unclear whether the blind method was used, and random conceals were not reported. ^dThere are operational differences in the clinical symptom score rules. ^eTwo studies adopted the random number table method, but it was not clear whether the blind method was adopted. ^fThe experimental data units of one study differed from those of the other studies. ^gSmall sample size. ^hLow event rate.