Mechanical Study of Jian-Gan-Xiao-Zhi Decoction on Nonalcoholic Fatty Liver Disease Based on Integrated Network Pharmacology and Untargeted Metabolomics

<div>(a) The number of active ingredients of each herb in JGXZ obtained from TCMSP (OB ≥ 30%, DL ≥ 0.18) and BATMAN-TCM(score cutoff ≥20). (b) Veen diagram of compound targets of JGXZ and NAFLD-related targets. (c) Drug-component-disease-target network (Red diamond nodes represented the active ingredient in JGXZ and blue rectangle nodes represented the potential targets). (d) Overview of potential targets of JGXZ on NAFLD pathway (map04932) based on KEGG analysis (the potential targets are shown in red).</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 2: Mechanical Study of Jian-Gan-Xiao-Zhi Decoction on Nonalcoholic Fatty Liver Disease Based on Integrated Network Pharmacology and Untargeted Metabolomics 

Figure 2 | Mechanical Study of Jian-Gan-Xiao-Zhi Decoction on Nonalcoholic Fatty Liver Disease Based on Integrated Network Pharmacology and Untargeted Metabolomics 