Effect of Chaihu Shugan Pills on the Pharmacokinetics of Duloxetine and its Metabolite 4-Hydroxyduloxetine in Beagle Dogs: A Herb-Drug Interaction Study

<div>Chromatograms of duloxetine and its metabolite 4-hydroxyduloxetine. (a) Blank beagle dog plasma; (b) a blank beagle dog plasma spiked with duloxetine, 4-hydroxyduloxetine, and IS; (c) a plasma sample from a beagle dog.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 3

Figure 3: Effect of Chaihu Shugan Pills on the Pharmacokinetics of Duloxetine and its Metabolite 4-Hydroxyduloxetine in Beagle Dogs: A Herb-Drug Interaction Study 

Figure 3 | Effect of Chaihu Shugan Pills on the Pharmacokinetics of Duloxetine and its Metabolite 4-Hydroxyduloxetine in Beagle Dogs: A Herb-Drug Interaction Study 