Sweet Wormwood and Tortoise Shell Decoction (Thanh Hao Miet Giap Thang) Induces DNA Damage, S-Phase Arrest, and Apoptosis in MCF-7 Cells via ATR-CHK1 Signaling Pathway

<div>THMGT induced the apoptosis of MCF-7 cells. MCF-7 cells were treated with THMGT at a concentration of 3 mg/ml for 3, 6, and 9 h Annexin V/PI staining was performed to detect apoptosis. The lower right quadrant of the fluorescence activated cell sorting (FACS) output indicates the percentage of early apoptotic cells (Annexin V-stained cells), while the upper right quadrant indicates the percentage of late apoptotic cells (Annexin V+/PI-stained cells).</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 5

Figure 5: Sweet Wormwood and Tortoise Shell Decoction (Thanh Hao Miet Giap Thang) Induces DNA Damage, S-Phase Arrest, and Apoptosis in MCF-7 Cells via ATR-CHK1 Signaling Pathway 

Figure 5 | Sweet Wormwood and Tortoise Shell Decoction (Thanh Hao Miet Giap Thang) Induces DNA Damage, S-Phase Arrest, and Apoptosis in MCF-7 Cells via ATR-CHK1 Signaling Pathway 