Sweet Wormwood and Tortoise Shell Decoction (Thanh Hao Miet Giap Thang) Induces DNA Damage, S-Phase Arrest, and Apoptosis in MCF-7 Cells via ATR-CHK1 Signaling Pathway

<div>THMGT triggered DDR in MCF-7 cells. (a) The cells were treated with THMGT at a concentration of 3 mg/ml for 3, 6, and 9 h Collected cells were analyzed for the expressed levels of ATR, pCHK1, CHK1, pTP53, TP53, MDM2, and <i>γ</i>-H2AX by western blot. <i>β</i>-Actin expressions were measured as internal controls to show equal protein loading. The data presented are representatives of three independent experiments with similar results. 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Evidence-Based Complementary and Alternative Medicine

fig6

Figure 6

Figure 6: Sweet Wormwood and Tortoise Shell Decoction (Thanh Hao Miet Giap Thang) Induces DNA Damage, S-Phase Arrest, and Apoptosis in MCF-7 Cells via ATR-CHK1 Signaling Pathway 

Figure 6 | Sweet Wormwood and Tortoise Shell Decoction (Thanh Hao Miet Giap Thang) Induces DNA Damage, S-Phase Arrest, and Apoptosis in MCF-7 Cells via ATR-CHK1 Signaling Pathway 