Research Article
[Retracted] Role of miR-584-5p in Lipopolysaccharide-Stimulated Human Bronchial Epithelial Cell Inflammation and Apoptosis
Figure 2
Effects of miR-584-5p on lipopolysaccharide (LPS)-stimulated 16-HBE cell injury. (a) 16-HBE cells were transfected with mimic negative control (mimicNC), mimic miR-584-5p (mimic584), inhibitor negative control (inhibitorNC), or inhibitor miR-584-5p (inhibitor584) for 24 h and then stimulated with LPS (100 µg/mL) for 24 h. The mRNA expression of IL-1, IL-6, IL-8, TNF-α, MCP-1, and MIP-1α in 16-HBE cells was measured using qRT-PCR. GAPDH served as an internal control. p < 0.05 compared with the mimicNC, mimicNC + LPS, and mimic584 groups; #p < 0.05 compared with the mimicNC and mimic584 groups. (b)p < 0.05 compared with the inhibitorNC, inhibitor584, and inhibitorNC + LPS groups. The experiments were performed at least three times independently. Data are presented as mean ± standard deviation (SD).
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