Research Article
[Retracted] Role of miR-584-5p in Lipopolysaccharide-Stimulated Human Bronchial Epithelial Cell Inflammation and Apoptosis
Figure 3
Effect of miR-584-5p on inflammation in lipopolysaccharide (LPS)-stimulated 16-HBE cells. 16-HBE cells were transfected with mimic negative control (mimicNC), mimic miR-584-5p (mimic584), inhibitor negative control (inhibitorNC), or inhibitor miR-584-5p (inhibitor584) for 24 h and then treated with LPS (100 µg/mL) for 24 h. The expression of IL-1, IL-6, IL-8, TNF-α, MCP-1, and MIP-1α in the transfected 16-HBE cells was measured using western blotting. p < 0.05 compared with the mimicNC group; #p < 0.05 compared with the mimic584, mimicNC + LPS, and mimic 584 + LPS groups; △p < 0.05 compared with the mimicNC, mimic584, and mimicNC + LPS groups; ▲p < 0.05 compared with the mimicNC and mimic584 groups. p < 0.05 compared with the inhibitorNC, inhibitor584, and inhibitorNC + LPS groups; #p < 0.05 compared with the inhibitorNC, inhibitorNC + LPS, and inhibitor584 + LPS groups; △p < 0.05 compared with the inhibitorNC and inhibitor584 groups; ▲p < 0.05 compared with the inhibitor584, inhibitorNC + LPS, and inhibitor584 + LPS groups. The experiments were performed at least three times independently. Data are presented as mean ± standard deviation (SD).