Protective Effects of Astragaloside IV on Uric Acid-Induced Pancreatic <i>β</i>-Cell Injury through PI3K/AKT Pathway Activation

<div>AS-IV promoted glucose-induced insulin secretion in Min6 cells. Min6 cells were stimulated with AS-IV, UA, and low or high concentrations of glucose. The cells were divided into six groups: control, UA, UA + DMSO, UA ± 12.5 <i>μ</i>mol/l AS-IV, UA + 25 <i>μ</i>mol/l AS-IV, and UA + 50 <i>μ</i>mol/l AS-IV groups. Insulin release was determined using the GSIS assay. Data are expressed as mean ± SD. 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Evidence-Based Complementary and Alternative Medicine

fig3

Figure 3

Figure 3: Protective Effects of Astragaloside IV on Uric Acid-Induced Pancreatic <i>β</i>-Cell Injury through PI3K/AKT Pathway Activation 

Evidence-Based Complementary and Alternative Medicine

Protective Effects of Astragaloside IV on Uric Acid-Induced Pancreatic β-Cell Injury through PI3K/AKT Pathway Activation

Figure 3