Screening of Biomarkers and Quality Control of Shaoyao Gancao Decoction Using UPLC-MS/MS Combined with Network Pharmacology and Molecular Docking Technology

Table 6

Calibration curves of the analytes.

Analytes	Calibration curve	Linear rang (ng.μL^−1)	r	LOQ (ng/μL^−1)
Hesperidin	Y = 2E + 06X + 6462	0.0392∼0.98	0.9992	0.01
Naringenin	Y = 2E + 06X − 3159	0.0384∼0.96	0.9985	0.01
Liquiritin	Y = 3E + 06X + 4E + 04	1.432∼35.8	0.9979	0.04
Glycyrrhizic acid	Y = 835033X + 1E + 04	4.62∼115.5	0.9825	1.20
Liquiritigenin	Y = 7E + 06X + 4E + 04	0.554∼13.9	0.9990	0.12
Isoliquiritin	Y = 4E + 06X  +  20213	0.201∼5.025	0.9998	0.05
Isoliquiritin apioside	Y = 2E + 06X  + 50766	0.776∼19.4	1.0000	0.02
Caffeic acid	Y = 1E + 07X  + 27935	0.036∼0.09	0.9988	0.01
Ferulic acid	Y = 1E + 06X  + 7406	0.006∼0.15	0.9985	0.002
Coniferyl ferulate	Y = 625840X  + 3624	0.008∼0.20	0.9989	0.002
Albiflorin	Y = 33658X  + 44760	2.74∼68.00	0.9978	0.68
Gallic acid	Y = 4E + 07X  + 3E + 04	0.132∼3.30	0.9997	0.33
Methyl gallate	Y = 1E + 07X  + 9012	0.008∼0.20	0.9999	0.002
Benzoyl paeoniflorin	Y = 24147X − 2883.4	0.42∼10.50	0.9991	0.11
Narirutin	Y = 2E + 06X  + 1108	0.008∼0.20	0.9999	0.002
Chlorogenic acid	Y = 6E + 06X  + 6980	0.0024∼0.06	0.9990	0.001
Neochlorogenic acid	Y = 5E + 06X  + 2745	0.0032∼0.08	0.9995	0.001
Rutin	Y = 1E + 06X  + 7917	0.0012∼0.03	0.9994	0.001
1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose	Y = 1E + 06X  + 3214	0.0010∼0.025	0.9995	0.001