Research Article
Exploring Active Compounds and Mechanisms of Angong Niuhuang Wan on Ischemic Stroke Based on Network Pharmacology and Molecular Docking
Table. 2
The information of the core targets.
| Gene | Degree | Betweenness centrality |
| IL-6 | 91 | 0.030325537 | AKT1 | 81 | 0.018339264 | CXCL12 | 73 | 0.018125697 | MAPK3 | 68 | 0.009734912 | CXCR4 | 66 | 0.015168905 | PIK3CA | 65 | 0.012205642 | TNF | 61 | 0.00919471 | AGT | 59 | 0.008882338 | MMP9 | 53 | 0.006325729 | IL1B | 51 | 0.0066625 | ALB | 51 | 0.007447992 | PPBP | 45 | 0.003930831 | PF4 | 42 | 0.002706756 | BDNF | 40 | 0.003798139 | NOS3 | 39 | 0.003217693 | TLR4 | 38 | 0.002216187 | AGTR1 | 37 | 0.004279922 | CREB1 | 33 | 0.0019083 | F2 | 32 | 0.002232586 | CASP3 | 31 | 0.000874129 | APOB | 29 | 0.002920764 | SIRT1 | 28 | 0.000753076 | APOE | 25 | 0.001338523 | VWF | 25 | 0.001087882 | AVP | 22 | 0.000773649 |
|
|