Exploring Active Compounds and Mechanisms of Angong Niuhuang Wan on Ischemic Stroke Based on Network Pharmacology and Molecular Docking

Table 4

List of core ingredients in the top 20.

Active components	Herbs	Degree	Betweenness centrality
Quercetin	Coptidis Rhizoma, Gardeniae Fructus	54	0.056874662
β-estradiol	Moschus	51	0.078777286
Tyrosine	Bubali Cornu	44	0.045643145
Berberine	Coptidis Rhizoma	40	0.018811059
Wogonin	Scutellariae Radix	39	0.021360805
Beta-sitosterol	Scutellariae Radix, Gardeniae Fructus, Curcumae Radix	37	0.019391773
Baicalein	Scutellariae Radix	36	0.016063119
Tetrandrine	Coptidis Rhizoma	35	0.013666927
chrysin	Gardeniae Fructus	34	0.013739355
Baicalin	Scutellariae Radix	32	0.008324522
Acacetin	Scutellariae Radix	31	0.013057
Oroxylin a	Scutellariae Radix	31	0.022607
Kaempferol	Gardeniae Fructus	31	0.009087
Demethoxycurcumin	Curcumae Radix	30	0.014592
Stigmasterol	Scutellariae Radix, Gardeniae Fructus	29	0.017506
Oleanolic acid	Bovis Calculus, Gardeniae Fructus, Borneolum	28	0.008257
Serine	Bubali Cornu, Moschus, Margarita	28	0.006694
Linoleic acid	Scutellariae Radix, Gardeniae Fructus, Curcumae Radix	27	0.010942
Oleic acid	Gardeniae Fructus, Curcumae Radix	26	0.012292
Ammidin	Gardeniae Fructus	26	0.011124