The Effects of Probiotics Supplementation on Clinical Status and Biomarkers of Oxidative Damage and Inflammation in Children with Brucellosis: A Randomized, Double-Blind, and Placebo-Controlled Trial

Table 3

Biochemical parameters at baseline and after the 8-week intervention in children with brucellosis that received either probiotics or placebo.

Variables	Placebo group (n = 18)		Probiotics group (n = 19)
	Baseline	Week 8	Baseline	Week 8
Hs-CRP (mg/L)	16.7 ± 6.8	6.5 ± 3.5	16.5 ± 6.9	5.6 ± 2.5	0.13
TAC (mmol/L)	330.1 ± 53.8	762.9 ± 69.5	324.5 ± 91.7	1043.1 ± 126.8	<0.001
GSH (µmol/L)	664.1 ± 189.6	743.1 ± 209.6	540.5 ± 87.1	608.0 ± 84.8	0.60
MDA (µmol/L)	7.7 ± 0.7	4.2 ± 0.4	7.3 ± 0.9	3.4 ± 1.0	0.002

¹Obtained from ANCOVA (values are adjusted for baseline values and age). GSH, total glutathione; hs-CRP, high-sensitivity C-reactive protein; MDA, malondialdehyde; TAC, total antioxidant capacity.