A Study of the Protective Effect of Bushen Huoxue Prescription on Cerebral Microvascular Endothelia Based on Proteomics and Bioinformatics

Figure 2

Proteomic analysis results for BSHX-altered proteins. (a) Venn diagram showing numerical distribution of proteins identified in different bEnd.3 cell lysates by the nanoLC-LTQ-Orbitrap MS/MS approach. Cells were treated with vehicle (control group: Con), 300 μg/mL of AGEs (model group: Mo), and AGEs with 100 mg/L of BSHX (high-concentration BSHX treatment group: FF) for 72 h respectively. (b–d) Proteins significantly upregulated and downregulated by BSHX were classified according to the cellular component (b), molecular function (c), and biological process (d).

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