Research Article
A Study of the Protective Effect of Bushen Huoxue Prescription on Cerebral Microvascular Endothelia Based on Proteomics and Bioinformatics
Figure 3
Bioinformatics analysis of the signaling networks negatively regulated by BSHX. (a) Interaction network of protein groups downregulated by BSHX. (b) Pathway enrichment analysis of the differentially expressed proteins predicted the significantly canonical pathways targeted by BSHX in AGE-stimulated bEnd.3 cells. The gray columns on the left Y-axis represent the number of identified proteins in each pathway. The green columns on the right Y-axis depict the percentage of identified proteins over the total proteins in that pathway. (c) BP enrichment analysis for differentially expressed proteins in BSHX-treated bEnd.3 cells. , , relative to the model group.
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