The Clinical Effect and Mechanism of Prostant on Urinary Retention and Anal Pain

Figure 4

Prostant exerted analgesic effect on mice. H&UR model mice were introduced with 0.6% glacial acetic acid, and then the number of writhing reactions (a) and the inhibition ratio of writhing response (b) were detected. In addition, H&UR model mice were pressed and analyzed at 0.5 h, 1h, and 2h after administration. The threshold of pain (c) and the increased ratio threshold of pain (d) were determined. Besides, the foot plantar aponeurosis of H&UR model mice was injected with 1% fresh egg white to cause inflammation. The degree of swelling (e) and the inhibition rate of inflammation (f) were assessed. The means ± SD of six independent samples were displayed. In Figures (a) and (e), v.s control group, and v.s H&UR model group. In Figure (c), v.s that at 0 h, and v.s low-dose prostant at the same time point, respectively. In Figures (d) and (f), and v.s low-dose prostant at the same time point, respectively.

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