[Retracted] KCNQ1OT1 Influences HK-2 Apoptosis and Inflammation in LPS-Induced Acute Renal Injury via Modulating miR-30a-5p/NLRP3 Axis

Figure 5

KCNQ1OT1 regulates the expression of NLRP3 by targeting miR-30a-5p. (a) The binding sites of KCNQ1OT1 and miR-30a-5p predicted by LncBase Predicted v.2. (b) The binding sites of miR-30a-5p and NLRP3 predicted by TargetScan. (c) Detection of luciferase activity after co-transfection of miR-NC or miR-30a-5p and KCNQ1OT1 reporter plasmid into HK-2 cells. (d) Detection of luciferase activity after co-transfection of miR-NC or miR-30a-5p and NLRP3 reporter plasmid into HK-2 cells. (e) miR-30a-5p expression in HK-2 cells detected by RT-qPCR. (f) NLRP3 expression detected by Western blot.

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