Baicalin Ameliorates DSS-Induced Colitis by Protecting Goblet Cells through Activating NLRP6 Inflammasomes

Figure 4

Baicalin activates NLRP6 inflammasomes. The mRNA expression levels of NLRP6 (a), ASC (b), caspase-1 (c), and IL-18 (d) in colon tissue. (e–g) The protein levels of NLRP6 and caspase-1 in colon tissue determined by Western blotting. (h, i) Representative images of immunohistochemical staining of NLRP6 and the quantification of NLRP6 by ImageJ. (j) Representative images of immunohistochemical staining of IL-18. Scale bar: 100 μm. Data are presented as mean ± SEM (n ≥ 5). vs. DSS group; vs. DSS group.

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