Qige Huxin Formula Attenuates Isoprenaline-Induced Cardiac Fibrosis in Mice via Modulating Gut Microbiota and Protecting Intestinal Integrity

Figure 3

QHF alleviated cardiac fibrosis and decreased inflammation in mice with CF. ((a, b, c) × 400) Representative images of cardiac fibrosis reflected by HE, Masson, and immunohistochemical staining. (d) The myocyte cross section area. (e, f) Quantification of interstitial fibrosis and α-SMA (n = 6). (g, h) (i) Levels of TNF-α, IL-1β, and IL-6 in serum (n = 8). Data are presented as mean ± SD. versus the control group; ^### versus the model group.

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