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Evidence-Based Complementary and Alternative Medicine
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Evidence-Based Complementary and Alternative Medicine
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2022
/
Article
/
Tab 3
/
Research Article
Study on the Potential Mechanism of
Semen Strychni
against Myasthenia Gravis Based on Network Pharmacology and Molecular Docking with Experimental Verification
Table 3
Vina affinity of ingredient-target docking.
Compound
Affinity (kcal/mol)
AKT1
MAPK1
MAPK14
CHRM1
ACHE
CHRNA4
Isobrucine
−6.8
/
−7.6
−7.4
/
−8.2
Vomicine
−8.3
/
/
−8.6
/
−9.1
(S)-Stylopine
/
−8.9
/
−8.3
−8.3
−9.6
Strychnine
/
/
−9.1
/
/
−9.7
Brucine-N-oxide
/
/
−8.5
/
/
−9.1
Brucine
/
/
/
−7.5
/
/
/: means did not analyze.