The Single-Nucleotide Polymorphism of miR-27a rs895819 and the Expression of miR-27a in Helicobacter pylori-Related Diseases and the Correlation with the Traditional Chinese Medicine Syndrome

Table 5

Correlation analysis between levels of miR-27a/miR-27a genotype and the severity of H. pylori infection and the grade of histopathology.

	Levels of miR-27a		miR-27a genotype
	Spearman’s		Spearman’s
Hp infection	−0.175	0.012	0.035	0.614
Gastric inflammation	−0.112	0.102	0.019	0.570
Inflammatory activity	−0.122	0.076	0.094	0.171
Gastric atrophy	−0.086	0.209	−0.068	0.326
Gastric intestinal metaplasia	−0.016	0.811	0.014	0.845
Gastric dysplasia	−0.117	0.089	0.002	0.972

The bold values mean that the levels of miR-27a have a negative correlation with Hp infection, and the correlation index is ‐0.175, which is statistically significant.