The Single-Nucleotide Polymorphism of miR-27a rs895819 and the Expression of miR-27a in Helicobacter pylori-Related Diseases and the Correlation with the Traditional Chinese Medicine Syndrome

Table 7

Multivariate logistic regression analysis in TCM syndrome groups.

	SSDH vs. NON		LSD vs. NON		SQD vs. NON		IBSB vs. NON
	OR (95% CI)		OR (95% CI)		OR (95% CI)		OR (95% CI)
Gender
Male	Ref	—	Ref	—	Ref	—	Ref	—
Female	1.42 (0.31–6.54)	0.649	2.78 (0.59–13.14)	0.198	2.30 (0.44–11.82)	0.317	9.30 (0.90–96.19)	0.061
H. pylori
Negative	Ref	—	Ref	—	Ref	—	Ref	—
Positive	9.69 (2.31–40.50)	0.002	20.98 (4.42–99.47)	0.001	5.33 (1.10–25.81)	0.038	—	0.988
Age
≤45	Ref	—	Ref	—	Ref	—	Ref	—
45∼54	0.30 (0.05–1.80)	0.187	0.30 (0.05–1.92)	0.205	0.10 (0.01–0.87)	0.037	0.12 (0.01–2.53)	0.171
55∼64	0.73 (0.06–9.36)	0.808	0.37 (0.03–5.01)	0.453	1.13 (0.08–15.91)	0.922	1.40 (0.06–32.43)	0.833
≥65	0.16 (0.02–1.26)	0.083	0.09 (0.01–0.76)	0.027	0.42 (0.05–3.50)	0.420	—	0.989
miR-27a (rs895819) genotype
TT	Ref	—	Ref	—	Ref	—	Ref	—
CT	1.02 (0.24–4.28)	0.976	1.10 (0.25–4.80)	0.898	1.72 (0.36–8.19)	0.495	4.41 (0.45–42.79)	0.201
CC	—	—	—	—	—	—	—	—
T	Ref	—	Ref	—	Ref	—	Ref	—
C	1.13 (0.36–3.55)	0.840	1.02 (0.32–3.28)	0.971	0.79 (0.23–2.73)	0.714	0.44 (0.09–2.24)	0.326

All the bold values represent that the outcome was statistically significant.