Research Article
[Retracted] Potential Progression Mechanism and Key Genes in Early Stage of mTBI
Table 2
Gene ontology (GO) and KEGG pathway enrichment analysis of differentially expressed genes (DEGs) with adjusted
and gene counts ≥10.
| Category | ID | Term | Adjusted | Count |
| Biological process | GO: 0002683 | Negative regulation of immune system process | 0.000130695 | 18 | Biological process | GO: 0002697 | Regulation of immune effector process | 0.000182696 | 16 | Biological process | GO: 0042060 | Wound healing | 0.000495285 | 16 | Biological process | GO: 0031960 | Response to corticosteroid | 0.000122132 | 15 | Biological process | GO: 0032496 | Response to lipopolysaccharide | 0.002612511 | 15 | Biological process | GO: 0008202 | Steroid metabolic process | 0.000130695 | 14 | Biological process | GO: 0051384 | Response to glucocorticoid | 0.000130695 | 14 | Biological process | GO: 0019216 | Regulation of lipid metabolic process | 0.000725406 | 14 | Biological process | GO: 0002443 | Leukocyte mediated immunity | 0.001029513 | 14 | Biological process | GO: 0001819 | Positive regulation of cytokine production | 0.003130079 | 14 | Biological process | GO: 0070661 | Leukocyte proliferation | 0.000819502 | 13 | Biological process | GO: 0007584 | Response to nutrient | 0.002465097 | 13 | Biological process | GO: 0001525 | Angiogenesis | 0.00904787 | 13 | Biological process | GO: 1903532 | Positive regulation of secretion by cell | 0.00914943 | 13 | Biological process | GO: 0050777 | Negative regulation of immune response | 4.29E − 05 | 12 | Biological process | GO: 0051048 | Negative regulation of secretion | 0.000819502 | 12 | Biological process | GO: 0031099 | Regeneration | 0.002267839 | 12 | Biological process | GO: 0050727 | Regulation of inflammatory response | 0.003740474 | 12 | Biological process | GO: 0002250 | Adaptive immune response | 0.004711657 | 12 | Biological process | GO: 0022407 | Regulation of cell-cell adhesion | 0.006702972 | 12 | Biological process | GO: 0002698 | Negative regulation of immune effector process | 4.72E − 05 | 11 | Cellular component | GO: 0009897 | External side of plasma membrane | 0.001830905 | 14 | Cellular component | GO: 0045177 | Apical part of the cell | 0.046821474 | 11 | Cellular component | GO: 0016324 | Apical plasma membrane | 0.039668583 | 10 | Molecular function | GO: 0048018 | Receptor ligand activity | 1.05E − 06 | 20 | Molecular function | GO: 0030545 | Receptor regulator activity | 1.93E − 06 | 20 | Molecular function | GO: 0005125 | Cytokine activity | 9.44E − 06 | 12 | Molecular function | GO: 0005126 | Cytokine receptor binding | 0.004590706 | 11 | KEGG pathway | rno04060 | Cytokine-cytokine receptor interaction | 0.01018118 | 12 | KEGG pathway | rno04080 | Neuroactive ligand-receptor interaction | 0.032342367 | 12 | KEGG pathway | rno05169 | Epstein-barr virus infection | 0.032342367 | 10 |
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