Pan-Cancer Analysis of BUB1B/hsa-miR-130a-3p Axis and Identification of Circulating hsa-miR-130a-3p as a Potential Biomarker for Cancer Risk Assessment

Figure 5

Differentially expressed miRNAs (DEmiRNAs) exploring and analysis. (a) Volcano plot of DEmiRNAs from PP-NN set. (b) Volcano plot of DEmiRNAs from PP-PN set. (c) Venn plot of DEmiRNAs from the above 2 comparisons. (d) Results of disease enrichment analysis of overlapped DEmiRNAs from 2 sets using miEAA. (e) Results of KEGG enrichment analysis of overlapped DEmiRNAs from 2 sets using mirPath. (f) Upset plot of overlapped DEmiRNAs and predicted miRNAs targeting BUB1B using different online tools. (g and h) Expression pattern of hsa-miR-130a-3p in GSE142582 (g) and GSE55515 (h). Results of diseases enrichment analysis (i) and KEGG enrichment analysis (j) of hsa-miR-130a-3p using CancerMIRNome.

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