Evidence-Based Complementary and Alternative Medicine

Research Article

Network Pharmacology and Molecular Docking to Explore the Mechanism of Kangxian Decoction for Epilepsy

Table 1

Active ingredients of KXD.


Herb	ID	Molecule name	Molecular formula	CAS no.

BX: Pinellia ternata	BX1	Baicalin	C₂₁H₁₈O₁₁	21967-41-9
	BX2	Baicalein	C₂₂H₂₀O₁₁	491-67-8
	BX3	24-Ethylcholest-4-en-3-one	C₂₉H₄₈O	N/A
	BX4	Cavidine	C₂₁H₂₃NO₄	32728-75-9
	BX5	Coniferin	C₁₆H₂₂O₈	531-29-3
	BX6	Ephedrine	C₁₀H₁₅NO	299-42-3
	BX7	Coniine	C₈H₁₇N	458-88-8

DL: Pheretima	DL1	Succinic acid	C₄H₆O₄	110-15-6
	DL2	Xanthine	C₅H₄N₄O₂	69-89-6
	DL3	Adenine	C₅H₅N₅	73-24-5
	DL4	Valine	C₅H₁₁NO₂	72-18-4
	DL5	Leucine	C₆H₁₃NO₂	61-90-5

GT: Uncaria	GT1	Akuammicine	C₂₀H₂₂N₂O₂	639-43-0
	GT2	Angustidine	C₁₉H₁₅N₃O	40217-50-3
	GT3	Corynantheine	C₂₂H₂₆N₂O₃	18904-54-6
	GT4	Corynoxeine	C₂₂H₂₆N₂O₄	630-94-4
	GT5	Dihydrocorynantheine	C₂₂H₂₈N₂O₃	50439-68-4
	GT6	Geissoschizine methyl ether	C₂₂H₂₆N₂O₃	60314-89-8
	GT7	Hirsuteine	C₂₂H₂₆N₂O₃	35467-43-7
	GT8	Isocorynoxeine	C₂₂H₂₆N₂O₄	51014-29-0
	GT9	Isopteropodine	C₂₁H₂₄N₂O₄	5171-37-9
	GT10	Isorhynchophylline	C₂₁H₂₆N₂O₄	144525-05-3
	GT11	Rhynchophylline	C₂₂H₂₈N₂O₄	76-66-4
	GT12	Vallesiachotamine	C₂₁H₂₂N₂O₃	5523-37-5
	GT13	Corynoxine	C₂₂H₂₈N₂O₄	6877-32-3
	GT14	Yohimbine	C₂₁H₂₆N₂O₃	146-48-5

SQ: Panax notoginseng	SQ1	Liquiritigenin	C₁₅H₁₂O₄	578-86-9
	SQ2	Panaxynol	C₁₇H₂₄O	81203-57-8
	SQ3	Ginsenoside rh2	C₃₆H₆₂O₈	78214-33-2
	SQ4	Dencichine	C₅H₈N₂O₅	5302-45-4
	SQ5	Methyl palmitate	C₁₇H₃₄O₂	112-39-0
	SQ6	Panaxytriol	C₁₇H₂₆O₃	N/A

SCP: Acorus tatarinowii	SCP1	8-Isopentenyl-kaempferol	C₂₀H₁₈O₆	28610-31-3
	SCP2	Beta-asarone	C₁₂H₁₆O₃	5273-86-9
	SCP3	Alpha-asarone	C₁₂H₁₆O₃	2883-98-9
	SCP4	Methyl isoeugenol	C₁₁H₁₄O₂	93-16-3

TM: Gastrodia elata	TM1	Vanillin	C₈H₈O₃	121-33-5
	TM2	4-Ethoxymethylphenyl-4′-hydroxybenzylether	C₁₆H₁₈O₃	77160-41-9
	TM3	Gastrodin	C₁₃H₁₈O₇	62499-27-8
	TM4	4-(4′-hydroxybenzyloxy)benzyl methyl ether	C₁₅H₁₆O₃	N/A
	TM5	Gastrodioside	C₂₀H₂₄O₈	77162-64-2
	TM6	N6-(4-hydroxybenzyl)-adenosine	C₁₇H₁₉N₅O₅	110505-75-4
BX、GT、SQ、TM	D	Daucosterol	C₃₅H₆₀O₆	474-58-8
BX、GT、SQ	B	Beta-sitosterol	C₂₉H₅₀O	83-46-5
BX、SQ	S	Stigmasterol	C₂₉H₄₈O	83-48-7
BX、SCP	C	Cycloartenol	C₃₀H₅₀O	469-38-5
DL、TM	P	Palmitic acid	C₁₆H₃₂O₂	57-10-3
GT、SQ	Q	Quercetin	C₁₅H₁₀O₇	117-39-5
GT、SCP	K	Kaempferol	C₁₅H₁₀O₆	520-18-3