Research Article
[Retracted] Identification of miRNA-mRNA Pairs in Relation to TNF-α/IL-1β Induced Inflammatory Response in Intervertebral Disc Degeneration
Table 2
The top 10 upregulated and downregulated DEGs between the cultured annulus cells treated with or without IL-1β (GSE27494).
| | Downregulated DEGs | GenBank accession | Ensembl gene ID | Log2FC | Adjust P |
| | PRSS23 | NM_007173 | ENSG00000150687 | 4.26 | 7.19E-06 | | CLEC3B | NM_003278 | ENSG00000163815 | 3.27 | 2.39E-05 | | C14orf139 | NM_152592 | ENSG00000176438 | 2.76 | 4.24E-05 | | CCDC109B | NM_017918 | ENSG00000005059 | 2.54 | 5.45E-05 | | SSX2IP | NM_001166294 | ENSG00000117155 | 2.08 | 8.93E-05 | | PLEKHA4 | NM_020904 | ENSG00000105559 | 2.03 | 9.48E-05 | | PCOLCE2 | NM_013363 | ENSG00000163710 | 1.54 | 1.58E-04 | | OLFML2B | NM_015441 | ENSG00000162745 | 1.44 | 1.77E-04 | | FBLN2 | NM_001004019 | ENSG00000163520 | 1.30 | 2.03E-04 | | LOC730101 | — | ENSG00000216775 | 1.15 | 2.39E-04 |
| | Upregulated DEGs | | LOC285628 | — | — | 7.70 | 9.91E-09 | | ZC3H12A | NM_025079 | ENSG00000163874 | 5.12 | 2.23E-06 | | RAB27B | NM_004163 | ENSG00000041353 | 4.71 | 3.98E-06 | | GLIS3 | NM_152629 | ENSG00000107249 | 4.70 | 3.99E-06 | | SLC7A2 | NM_001008539 | ENSG00000003989 | 4.58 | 4.72E-06 | | TREM1 | NM_018643 | ENSG00000124731 | 4.41 | 5.88E-06 | | CXCL5 | NM_002994 | ENSG00000163735 | 4.24 | 7.30E-06 | | LIF | NM_002309 | ENSG00000128342 | 4.21 | 7.58E-06 | | STC1 | NM_003155 | ENSG00000159167 | 4.21 | 7.66E-06 | | PID1 | NM_001100818 | ENSG00000153823 | 4.20 | 7.68E-06 |
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