Active Compounds and Targets of Yuanzhi Powder in Treating Alzheimer’s Disease and Its Relationship with Immune Infiltration Based on HPLC Fingerprint and Network Pharmacology

<div>Fingerprint of Yuanzhi Powder (YZP) and AD differential genes (DEGs) screening. (a) Fingerprinting of YZP. Peak 5- 3,6′-disinapoylsucrose, peak 14- coptisine, peak 15- palmatine, peak 16- berberine. (b) PCA analysis before batch effect removal. (c) PCA analysis following batch effect removal. (d) Volcano map for DEGs. Red nodes represent upregulated genes, blue nodes represent downregulated genes, and black nodes represent no DEGs. (e) Heatmap of DEGs from AD and normal tissue. Red indicates higher gene expression, and blue indicates lower gene expression.</div>

Evidence-Based Complementary and Alternative Medicine

fig1

Figure 1

Figure 1: Active Compounds and Targets of Yuanzhi Powder in Treating Alzheimer’s Disease and Its Relationship with Immune Infiltration Based on HPLC Fingerprint and Network Pharmacology 

Figure 1 | Active Compounds and Targets of Yuanzhi Powder in Treating Alzheimer’s Disease and Its Relationship with Immune Infiltration Based on HPLC Fingerprint and Network Pharmacology 