Baicalein Induces Apoptosis of Rheumatoid Arthritis Synovial Fibroblasts through Inactivation of the PI3K/Akt/mTOR Pathway

Figure 2

BAI promoted SW982 cell apoptosis. (a) Annexin V-FITC positive and PI-positive staining detected early apoptotic cells (lower right quadrant), Annexin V-FITC positive and PI-positive double staining detected late apoptotic cells (upper right quadrant), and Annexin V-FITC negative and PI-positive staining detected dead cells (upper left quadrant). (b) Quantitative data for (a). (c) Apoptosis-related proteins in SW982 cells were detected by western blotting. (d) Quantitative data for (c). , vs. 0 μM BAI group; and , vs. 15 μM BAI group; and , vs. 25 μM BAI group. n = 3.

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