Paclitaxel-Containing Extract Exerts Anti-Cancer Activity through Oral Administration in A549-Xenografted BALB/C Nude Mice: Synergistic Effect between Paclitaxel and Flavonoids or Lignoids

Table 3

The anti-cancer effect and adverse effect of HDS-1 on A549 xenograft-bearing mice.

Group	Administration dosage mg/kg	Mortality	Inhibition rate %	Survival rate %	Side effect
Vehicle	—	0	—	100	—
PTX I.P.	10	4	38.60 ± 64.87	66.7	Seroperitoneum and hematochezia
HDS-1 (H)	600	6	86.1 ± 12.94	54.55	—
HDS-1 (L)	200	1	65.7 ± 38.71	91.1	—
PTX + WAB	10 + 50	0	−17.6 ± 77.88	100	—