Aqueous Extract and Polysaccharide of Aconiti Lateralis Radix Induce Apoptosis and G0/G1 Phase Cell Cycle Arrest by PI3K/AKT/mTOR Signaling Pathway in Mesangial Cells

<div>HPLC fingerprint chromatogram of Aconiti Lateralis Radix extracts. (a) HPLC fingerprint chromatograms of the extracts of the reference standards. (b) Aconiti Lateralis Radix. In the chromatograms, (1) benzoylhypacoitine (PubChem CID:3047329); (2) benzoylmesaconine (PubChem CID:13343340); (3) mesaconitine (PubChem CID:416228); (4) benzoyl aconitine (PubChem CID:1221732); (5) aconitine (PubChem CID:245005); (6) hypaconitine (PubChem CID:441737).</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 1: Aqueous Extract and Polysaccharide of Aconiti Lateralis Radix Induce Apoptosis and G0/G1 Phase Cell Cycle Arrest by PI3K/AKT/mTOR Signaling Pathway in Mesangial Cells 

Figure 1 | Aqueous Extract and Polysaccharide of Aconiti Lateralis Radix Induce Apoptosis and G0/G1 Phase Cell Cycle Arrest by PI3K/AKT/mTOR Signaling Pathway in Mesangial Cells 