[Retracted] Identification of Potential Poly (ADP-Ribose) Polymerase-1 Inhibitors Derived from Rauwolfia serpentina: Possible Implication in Cancer Therapy

Table 2

Physicochemical properties of the selected ligands derived from R. serpentina.

Sl. no.	Name	Mol weight	cLog P	cLog S	H-acceptors	H-donors	Polar surface area	Drug-likeness	Mutagenic	Tumorigenic	Reproductive effective	Irritant	Rotatable bonds
1	Serpentinine	685.842	2.4747	−6.147	9	2	100.53	1.3453	None	None	None	None	7
2	Rescinnamine	634.723	3.9046	−4.816	11	1	117.78	0.21574	None	None	High	None	11
3	Rescinnamidine	636.739	4.0279	−4.681	11	1	117.78	-1.0959	None	None	High	None	12
4	Phytosterols	414.715	7.8552	−6.669	1	1	20.23	-4.475	None	None	None	None	6
5	Ajmalimine	520.624	3.5094	−5.118	8	1	80.7	3.4909	None	None	None	Low	7
6	Deserpidine	578.66	3.6454	−4.428	10	1	108.55	2.322	None	None	None	None	9
7	Ajmalicine	352.433	2.2674	−3.141	5	1	54.56	2.6043	None	None	None	None	2
8	Reserpine	608.686	3.5754	−4.446	11	1	117.78	2.322	None	None	High	None	10
9	Renoxidine	624.685	2.602	−2.277	12	1	131.61	-2.8747	None	None	High	None	10
10	Yohimbine	354.448	2.3512	−3.065	5	2	65.56	1.5035	None	None	None	None	2
11	Isorauhimbine	354.448	2.3512	−3.065	5	2	65.56	1.5035	None	None	None	None	2
12	Rauwolscine	354.448	2.3512	−3.065	5	2	65.56	1.5035	None	None	None	None	2
13	1,2-Dihydrovomilenine	352.433	1.8244	−3.654	5	2	61.8	1.1872	None	None	None	None	2