Elucidating the Neuroprotective Effect of Tecoma stans Leaf Extract in STZ-Induced Diabetic Neuropathy
Table 1
Effect of Tecoma stans extract on cold allodynia.
Normal Control
Diabetic Control
Gabapentin 50 mg/kg
TSE 200 mg/kg
TSE 300 mg/kg
TSE 400 mg/kg
TSE 400 mg/kg + Gabapentin
0 Week
4.42 ± 0.21
4.21 ± 0.51
4.65 ± 1.22
4.35 ± .051
4.55 ± 0.51
4.75 ± 1.6
4.71 ± 1.8
Week 1
4.45 ± .051
5.98 ± 1.82
5.45 ± 1.12
5.95 ± 1.74 +
5.91 ± 1.5 +
5.60 ± 0.40 ,+
5.49 ± 1.25
Week 2
4.65 ± 1.22
6.89 ± 1.25
5.15 ± 5.62
5.62 ± 1.72 ,+
5.71 ± 0.30 ,++
5.36 ± 1.87 ,+
5.16 ± 1.30
Week 3
4.63 ± 1.82
7.88 ± 1.92
4.85 ± 6.12
5.20 ± 0.41,+
5.25 ± .1.7 ,+
5.10 ± 1.67
5.05 ± 1.32
Week 4
4.55 ± 0.51
9.78 ± 1.52##
4.42 ± 1.52
4.93 ± 0.51##,,++
4.83 ± 1.12##,,+
4.69 ± 0.14
4.47 ± 0.68
Data are expressed as mean ± SD (n = 6). Data were statistically analyzed using two-way ANOVA followed by Tukey–Kramer’s multiple comparison test at ,, and . The values are expressed as # and ## compared with the normal control group at the 4th week; ,, and compared with the diabetic control group; +,++, and+++ compared with standard treatment Gabapentin.
