Elucidating the Neuroprotective Effect of Tecoma stans Leaf Extract in STZ-Induced Diabetic Neuropathy
Table 2
Effect of Tecoma stans extract on thermal hyperalgesia.
Normal Control
Diabetic Control
Gabapentin 50 mg/kg
TSE 200 mg/kg
TSE 300 mg/kg
TSE 400 mg/kg
TSE 400 mg/kg + Gabapentin
0 Week
4.21 ± 0.21
4.51 ± 0.51
4.83 ± 1.2
4.85 ± 1.22
4.73 ± 1.82
4.75 ± 1.6
4.81 ± 1.8
Week 1
4.32 ± .051
5.88 ± 1.82
5.42 ± 1.12
5.75 ± 1.74 +
5.85 ± 1.5 +
5.43 ± 0.40
5.34 ± 1.25 ,aa
Week 2
4.55 ± 1.22
6.59 ± 1.25
5.05 ± 2.62
5.72 ± 1.72,++
5.69 ± 2.30 ,++
5.29 ± 1.87 ,+
5.11 ± 1.30 ,aa
Week 3
4.53 ± 1.82
7.58 ± 1.92
4.95 ± 3.12
5.25 ± 0.41,++
5.23 ± .1.7 ,+
5.09 ± 1.67
5.01 ± 1.32,a
Week 4
4.35 ± 0.51
9.58 ± 1.52##
4.48 ± 1.52
4.92 ± 0.51##,,++
4.88 ± 1.12##,,+
4.75 ± 0.14#,
4.45 ± 0.68,aa
Data are expressed as mean ± SD (n = 6). Data were statistically analyzed using two-way ANOVA followed by Tukey–Kramer’s multiple comparison test at ,, and . The values are expressed as # and ## compared with the normal control group at the 4th week; ,, and compared with the diabetic control group; +,++, and +++ compared with standard treatment Gabapentin; and and compared with TSE 200 mg/kg.
