Bioassay’s Directed Isolation-Structure Elucidation and Molecular Docking of Triterpenes from Persea duthiei against Biologically Important Microbial Proteins

Figure 5

Putative binding interaction of compound 4 against fungal lanosterol 14α-demethylase enzyme. The amino acids LEU380, LEU383, and VAL311 in the hydrophobic core of the enzyme located in the active site are involved in the hydrophobic Van der Waals bonding with the hydrophobic residues of compound 4 [35].