Untargeted Metabolomics Analysis of Crocus cancellatus subsp. damascenus (Herb.) B. Mathew Stigmas and Their Anticarcinogenic Effect on Breast Cancer Cells

Table 1

GC-MS analysis of C. cancellatus subsp. damascenus stigmas ethanol extract. Safranal is shown in bold type.

Retention time (min)	Component name	% of total
5.25	Hydroxyacetone	0.33
6.16	2-Methyl-2-butenal	0.66
6.30	2-Methylbutyraldehyde	0.23
6.68	Glycolic acid, ethyl ester	0.31
6.80	Propanoic acid, 2-oxo-, methyl ester	0.93
7.78	Furfural	1.7
10.97	5-Methylfurfural	0.65
11.46	2, 3-Dihydro-3, 5-dihydroxy-6-methyl-4H-pyran-4-one	0.7
13.29	β-Isophorone	1.12
14.43	Resorcinol, 5-methyl-	0.92
15.79	α-Isophorone	0.42
16.42	4-Oxoisophorone	0.76
16.50	2-Hydroxyisophorone	0.49
16.80	2, 3-Dihydro-3, 5-dihydroxy-6-methyl-4H-pyran-4-one	2.2
17.17	2, 2, 6-Trimethyl-1, 4-cyclohexanedione	0.55
18.09	Safranal	0.93
18.80	Eucarvone	3.32
19.00	3, 5, 5-Trimethyl-2-hydroxy-1, 4-cyclohexadione-2-ene	1.45
19.41	2-Furancarboxaldehyde, 5-(hydroxymethyl)	10.22
21.18	Nepetalactone	0.42
21.52	2, 6, 6-Trimethyl-4-oxo-2-cyclohexen-1-carboxaldehyde	14.52
21.75	2-Methoxy-4, 4, 6-trimethylcyclohexa-2, 5-dien-1-one	1.83
23.30	2, 4, 4-Trimethyl-3-carboxaldehyde-5-hydroxy-2, 5-cyclohexadien-1-one	0.58
23.74	Methylcyclohexane	2.4
26.18	2, 4-bis (1,1-Dimethylethyl) phenol	2.14
27.47	Lauric acid	1.17
27.80	Octanoic anhydride	1.51
28.23	D-Allose	3.71
31.97	Myristic acid	0.89
34.05	Pentadecanoic acid	0.21
34.16	Diisobutyl phthalate	0.3
35.20	7, 9-Di-tert-butyl-1-oxaspiro (4, 5) deca-6, 9-diene-2, 8-dione	0.52
36.31	Palmitic acid	14.36
36.61	Palmitic acid, ethyl ester	0.34
37.52	Margaric acid	0.88
39.59	Linoleic acid	8.77
39.71	Linoleic acid	5.47
39.98	Stearic acid	3.04
43.16	4, 8, 12, 16-Tetramethylheptadecan-4-olide	0.25
43.67	Hexanedioic acid, bis (2-ethylhexyl) ester	0.19